A. Siedlecki is currently an Associate Professor in the Departments
of Surgery and Bioengineering at the Pennsylvania State University
College of Medicine in Hershey, PA. Dr. Siedlecki also holds
an appointment in the College of Engineering at University
Park PA and is a member of the Materials Research Institute
at Penn State.
received a B.S. degree in Biomedical Engineering from the
Milwaukee School of Engineering in 1991. Dr. Siedlecki then
went on to conduct graduate work in the laboratory of Dr.
Roger Marchant at Case Western Reserve University in Cleveland,
where he conducted research on development of novel techniques
for high-resolution probe microscopy studies of blood proteins.
While at Case, he received M.S. and Ph.D. degrees in 1994
and 1996, respectively, both in Biomedical Engineering. After
a brief period of postdoctoral work at CWRU, Dr. Siedlecki
accepted an Academic Fellow appointment as a joint industry/academic
postdoctoral researcher with Eli Lilly Pharmaceuticals and
the Department of Chemical Engineering and Materials Science
at the University of Minnesota. During this time, Dr. Siedlecki
used an array of microscopy and spectroscopy techniques to
study the mechanisms of aggregation of insulin.
joined the faculty of the Departments of Surgery and Bioengineering
at the Pennsylvania State University in 1999. While at Penn
State, he has established a laboratory to study cardiovascular
biomaterials using both basic science and applied research,
focusing primarily on the issues of coagulation and thrombosis
in response to blood-material contact, and was promoted to
Associate Professor in 2005. Dr. Siedlecki's major research
areas include mechanisms of biomaterial-induced blood coagulation,
development and testing of medical devices including ventricular
assist devices and artificial hearts, biocompatibility of
polyurethane biomaterials and applications of nanotechnology
to cardiovascular biomaterials. His interests in proteins
and cells at surfaces have led to collaborations in the areas
of orthopaedic biomaterials, regenerative medicine and drug
delivery for cancer imaging and therapies.
Dr. Siedlecki is funded by grants from the National Institutes
of Health, National Heart Lung and Blood Institute, the Johnson
and Johnson/PSU innovative technology program and the State
of Pennsylvania Department of Health. He has previously received
funding from the American Heart Association and the Life Sciences
Greenhouse of Central Pennsylvania Technology Development
Fund. Dr. Siedlecki has served as an ad-hoc reviewer for NIH
study sections in the areas of hematology and technology development
and is a member of the Editorial Board for the Journal of
Biomedical Materials Research A.